Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reelin, integrin and DAB1 interactions during embryonic cerebral cortical development.

Cerebral cortex (New York, N.Y. : 1991) - 1 Oct 2005

Schmid Ralf S, Jo Rebecca, Shelton Stephanie, Kreidberg Jordan A, Anton E S

Abstract excerpt

Extracellular matrix-like molecule reelin and cell surface adhesion receptors such as alpha3beta1 integrin can regulate neuronal migration and position in the developing cerebral cortex. Here we show that alpha3beta1 integrin binds to the N-terminal region of reelin, a site distinct from the region of reelin shown to associate with other reelin receptors such as VLDLR/ApoER2. Furthermore, Dab1, a member of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules, Neuronal
Share to Cell Movement

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cerebral Cortex

Share to Extracellular Matrix Proteins

Share to Immunoprecipitation

Share to Reelin Protein

Share to Serine Endopeptidases

Source

Identifiers

PMID: 15703255
DOI: 10.1093/cercor/bhi041

Genes

DAB1
VLDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reelin, integrin and DAB1 interactions during embryonic cerebral cortical development.PMID 15703255Read ↗

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1.Semantic proximity Read ↗

Tyrosine phosphorylation of Disabled-1 is essential for Reelin-stimulated activation of Akt and Src family kinases.Semantic proximity Read ↗

Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons.Semantic proximity Read ↗

Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus.Semantic proximity Read ↗

Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1.Semantic proximity Read ↗

ApoER2 and VLDLr are required for mediating reelin signalling pathway for normal migration and positioning of mesencephalic dopaminergic neurons.Semantic proximity Read ↗

Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration.Semantic proximity Read ↗

Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migration and laminar organization of the cerebral cortex.Semantic proximity Read ↗

The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development.Semantic proximity Read ↗

Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability.Semantic proximity Read ↗

Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins.Semantic proximity Read ↗

Reelin-induced tyrosine [corrected] phosphorylation of disabled 1 during neuronal positioning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.