Article
Dentate granule cells in reeler mutants and VLDLR and ApoER2 knockout mice.
Experimental neurology - 1 Jul 2002
Drakew Alexander, Deller Thomas, Heimrich Bernd, Gebhardt Carl, Del Turco Domenico, Tielsch Albrecht, Förster Eckart, Herz Joachim, Frotscher Michael
Abstract excerpt
We have studied the organization and cellular differentiation of dentate granule cells and their axons, the mossy fibers, in reeler mutant mice lacking reelin and in mutants lacking the reelin receptors very low density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2). We show that granule cells in reeler mice do not form a densely packed granular layer, but are loosely distributed throughout...
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