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Article

Reelin promotes peripheral synapse elimination and maturation.

Science (New York, N.Y.) - 1 Aug 2003

Quattrocchi Carlo C, Huang Cheng, Niu Sanyong, Sheldon Michael, Benhayon David, Cartwright Joiner, Mosier Dennis R, Keller Flavio, D'Arcangelo Gabriella

Abstract excerpt

Reelin is an extracellular protein that is crucial for layer formation in the embryonic brain. Here, we demonstrate that Reelin functions postnatally to regulate the development of the neuromuscular junction. Reelin is required for motor end-plate maturation and proper nerve-muscle connectivity,...

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Identifiers

PMID: 12893944
DOI: 10.1126/science.1082690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12893944-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Reelin promotes peripheral synapse elimination and maturation.PMID 12893944Read ↗

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The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development.Semantic proximity Read ↗

Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells.Semantic proximity Read ↗

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