Article
Novel genetic tools facilitate the study of cortical neuron migration.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2016
Cionni Megan, Menke Chelsea, Stottmann Rolf W
Abstract excerpt
Key facets of mammalian forebrain cortical development include the radial migration of projection neurons and subsequent cellular differentiation into layer-specific subtypes. Inappropriate regulation of these processes can lead to a number of congenital brain defects in both mouse and human, including lissencephaly and intellectual disability. The genes regulating these processes are still not all identified,...
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