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Article

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1.

Neuron - 18 Oct 2012

Sekine Katsutoshi, Kawauchi Takeshi, Kubo Ken-Ichiro, Honda Takao, Herz Joachim, Hattori Mitsuharu, Kinashi Tatsuo, Nakajima Kazunori

Abstract excerpt

Birthdate-dependent neuronal layering is fundamental to neocortical functions. The extracellular protein Reelin is essential for the establishment of the eventual neuronal alignments. Although this Reelin-dependent neuronal layering is mainly established by the final neuronal migration step called "terminal translocation" beneath the marginal zone (MZ), the molecular mechanism underlying the control by Reelin of...

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Identifiers

PMID: 23083738
DOI: 10.1016/j.neuron.2012.07.020
PMCID: PMC3479437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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