Article
Mutation of the p16/CDKN2 gene and loss of heterozygosity in malignant mucosal melanoma and adenoid cystic carcinoma of the head and neck.
International journal of oncology - 1 Nov 2007
Suzuki Norihisa, Onda Takeshi, Yamamoto Nobuharu, Katakura Akira, Mizoe Jun-etsu, Shibahara Takahiko
Abstract excerpt
The purpose of this study was to investigate the molecular biological characteristics of malignant mucosal melanoma (MMM) and adenoid cystic carcinoma (ACC) of the head and neck. We analyzed the common genetic abnormalities that may help to identify the loci in the genes involved in the development of MMM and ACC of the head and neck by PCR-LOH on chromosomes 1p, 6q, 9p, 10q, 11q, 12q, 17p, and 19q. LOH was...
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