Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary oral squamous cell carcinoma associated with CDKN2A germline mutation: a case report.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale - 5 Feb 2022

Jeong Ah-Reum, Forbes Kimberly, Orosco Ryan K, Cohen Ezra E W

Abstract excerpt

BACKGROUND: Germline CDKN2A mutations are a well-known cause of familial atypical multiple mole melanoma (OMIM #155601) and melanoma-pancreatic cancer syndrome (OMIM #606719). Increased risk of head and neck squamous cell carcinoma (HNSCC), particularly oral squamous cell carcinoma (OSCC) in those with germline CDKN2A mutations, has been described. However, screening for HNSCC is not a routine practice in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Head and Neck Neoplasms

Share to Mouth Neoplasms

Share to Neoplasm Recurrence, Local

Share to Skin Neoplasms

Share to Squamous Cell Carcinoma of Head and Neck

Source

Open in PubMed Open full text

Identifiers

PMID: 35123577
DOI: 10.1186/s40463-022-00556-y
PMCID: PMC8818223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary oral squamous cell carcinoma associated with CDKN2A germline mutation: a case report.PMID 35123577Read ↗

Germline Pathogenic Variants in Squamous Cell Carcinoma of the Head and Neck.Semantic proximity Read ↗

CDKN2A Gene Mutations: Implications for Hereditary Cancer SyndromesSemantic proximity Read ↗

Synchronous Basal Cell Carcinoma and Squamous Cell Carcinoma of Nasal Vestibule With Novel Unique Variants Identified by Whole-exome Sequencing.Semantic proximity Read ↗

Germline<i>CDKN2A</i>Mutation Status and Survival in Familial Melanoma CasesSemantic proximity Read ↗

Analysis of clinically relevant somatic mutations in high-risk head and neck cutaneous squamous cell carcinoma.Semantic proximity Read ↗

Increased prevalence of lung, breast, and pancreatic cancers in addition to melanoma risk in families bearing the cyclin-dependent kinase inhibitor 2A mutation: implications for genetic counseling.Semantic proximity Read ↗

CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic naevi and internal malignancies: a case series and review of the literature.Semantic proximity Read ↗

Molecular characterization of oral squamous cell carcinoma using targeted next‐generation sequencingSemantic proximity Read ↗

Melanoma-prone families: new evidence of distinctive clinical and histological features of melanomas in CDKN2A mutation carriers.Semantic proximity Read ↗

Genotype-phenotype correlations for pancreatic cancer risk in Dutch melanoma families with pathogenic CDKN2A variants.Semantic proximity Read ↗

A Japanese case of familial malignant melanoma with germline CDK4 variant incidentally diagnosed by cancer genome profiling.Semantic proximity Read ↗

Development of esophageal squamous cell cancer in patients with FAMMM syndrome: Two clinical reports.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.