Article
Abnormalities of tumor suppressor genes P16 and P15 in primary maxillofacial squamous cell carcinomas.
Cancer genetics and cytogenetics - 1 Jul 1999
Zhao Y, Zhang S, Fu B, Xiao C
Abstract excerpt
As members of the same gene family, tumor suppressor genes P16/CDKN2/INK4A and P15/INK4B have a high degree of structural and functional homology with both P16 and P15 proteins involved directly in the regulation of cell cycles. However, the status of P16 and P15 genes in primary maxillofacial squamous cell carcinomas (MSCC) has not been reported. Studies on abnormalities of these genes including homozygous...
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