Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.

American journal of human genetics - 1 Nov 2004

Hodgkinson Colin A, Goldman David, Jaeger Judith, Persaud Shalini, Kane John M, Lipsky Robert H, Malhotra Anil K

Abstract excerpt

Schizophrenia, schizoaffective disorder, and bipolar disorder are common psychiatric disorders with high heritabilities and variable phenotypes. The Disrupted in Schizophrenia 1 (DISC1) gene, on chromosome 1q42, was originally discovered and linked to schizophrenia in a Scottish kindred carrying a balanced translocation that disrupts DISC1 and DISC2. More recently, DISC1 was linked to schizophrenia, broadly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Nerve Tissue Proteins

Share to North America

Share to Psychotic Disorders

Share to Schizophrenia

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 15386212
DOI: 10.1086/425586
PMCID: PMC1182115

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.PMID 15386212Read ↗

Positive association of the Disrupted-in-Schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population.Semantic proximity Read ↗

Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population.Semantic proximity Read ↗

Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder.Semantic proximity Read ↗

The DISC locus in psychiatric illness.Semantic proximity Read ↗

Genetic association between schizophrenia and the DISC1 gene in the Scottish population.Semantic proximity Read ↗

Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.Semantic proximity Read ↗

Limited association between Disrupted in Schizophrenia 1 (DISC1) gene and bipolar disorder in the Chinese population.Semantic proximity Read ↗

Disrupted-in-Schizophrenia-1.Semantic proximity Read ↗

Association study of three microsatellite polymorphisms located in introns 1, 8, and 9 of DISC1 with schizophrenia in the Chinese Han population.Semantic proximity Read ↗

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Association between variations in the disrupted in schizophrenia 1 gene and schizophrenia: A meta-analysis.Semantic proximity Read ↗

Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.