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Article

Homozygosity by descent mapping of blood pressure in the Old Order Amish: evidence for sex specific genetic architecture.

BMC genetics - 1 Oct 2007

McArdle Patrick F, Dytch Harvey, O'Connell Jeffery R, Shuldiner Alan R, Mitchell Braxton D, Abney Mark

Abstract excerpt

BACKGROUND: High blood pressure is a well established risk factor for morbidity and mortality acting through heart disease, stroke and cardiovascular disease. Genome wide scans have linked regions of nearly every human chromosome to blood pressure related traits. We have capitalized on beneficial qualities of the Old Order Amish of Lancaster, PA, a closed founder population with a relatively small number of...

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Identifiers

PMID: 17908314
DOI: 10.1186/1471-2156-8-66
PMCID: PMC2071912

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DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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