Article
Dynamic genetic linkage of intermediate blood pressure phenotypes during postural adaptations in a founder population.
Physiological genomics - 15 Feb 2013
Arenas I A, Tremblay J, Deslauriers B, Sandoval J, Šeda O, Gaudet D, Merlo E, Kotchen T, Cowley A W, Hamet P
Abstract excerpt
Blood pressure (BP) is a dynamic phenotype that varies rapidly to adjust to changing environmental conditions. Standing upright is a recent evolutionary trait, and genetic factors that influence postural adaptations may contribute to BP variability. We studied the effect of posture on the genetics of BP and intermediate BP phenotypes. We included 384 sib-pairs in 64 sib-ships from families ascertained by...
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