Article
Genome-wide mapping of human loci for essential hypertension.
Lancet (London, England) - 21 Jun 2003
Caulfield Mark, Munroe Patricia, Pembroke Janine, Samani Nilesh, Dominiczak Anna, Brown Morris, Benjamin Nigel, Webster John, Ratcliffe Peter, O'Shea Suzanne, Papp Jeanette, Taylor Elizabeth, Dobson Richard, Knight Joanne, Newhouse Stephen, Hooper Joel, Lee Wai, Brain Nick, Clayton David, Lathrop G Mark, Farrall Martin, Connell John
Abstract excerpt
BACKGROUND: Blood pressure may contribute to 50% of the global cardiovascular disease epidemic. By understanding the genes predisposing to common disorders such as human essential hypertension we may gain insights into novel pathophysiological mechanisms and potential therapeutic targets. In the Medical Research Council BRItish Genetics of HyperTension (BRIGHT) study, we aim to identify these genetic factors by...
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