Article
Genome-wide linkage scan for genes affecting longitudinal trends in systolic blood pressure.
BMC genetics - 31 Dec 2003
Jacobs Kevin B, Gray-McGuire Courtney, Cartier Kevin C, Elston Robert C
Abstract excerpt
Only one genome scan to date has attempted to make use of the longitudinal data available in the Framingham Heart Study, and this attempt yielded evidence of linkage to a gene for mean systolic blood pressure. We show how the additional information available in these longitudinal data can be utilized to examine linkages for not only mean systolic blood pressure (SBP), but also for its trend with age and its...
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