Article
Genotype-by-sex interaction in the aetiology of type 2 diabetes mellitus: support for sex-specific quantitative trait loci in Hypertension Genetic Epidemiology Network participants.
Diabetologia - 1 Oct 2006
Avery C L, Freedman B I, Kraja A T, Borecki I B, Miller M B, Pankow J S, Arnett D, Lewis C E, Myers R H, Hunt S C, North K E
Abstract excerpt
AIMS/HYPOTHESIS: While there are sex-related differences in both the prevalence of type 2 diabetes mellitus and disease risk factors, there is only limited research on sex-specific influences on type 2 diabetes aetiology within the same study population. Thus, we assessed genotype-by-sex interaction using a liability threshold model in an attempt to localise sex-specific type 2 diabetes quantitative trait loci...
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