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Article

Glutamine tract length of human androgen receptors affects hormone-dependent and -independent prostate cancer in mice.

Human molecular genetics - 1 Jan 2008

Albertelli Megan A, O'Mahony Orla A, Brogley Michele, Tosoian Jeffrey, Steinkamp Mara, Daignault Stephanie, Wojno Kirk, Robins Diane M

Abstract excerpt

The androgen receptor (AR) is involved in the initiation and progression of prostate cancer and its transition to androgen independence. Genetic variation in AR may contribute to disease risk and has been studied for a polymorphic N-terminal glutamine (Q) tract that shows population heterogeneity. While the length of this tract is known to affect AR in vitro, association with disease is complicated by genetic and...

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Identifiers

PMID: 17906287
DOI: 10.1093/hmg/ddm287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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