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Article

Length of the human androgen receptor glutamine tract determines androgen sensitivity in vivo.

Molecular and cellular endocrinology - 6 Aug 2011

Simanainen Ulla, Brogley Michele, Gao Yan Ru, Jimenez Mark, Harwood D Tim, Handelsman David J, Robins Diane M

Abstract excerpt

A well established functional polymorphism of the human androgen receptor (hAR) is the length of AR's N-terminal glutamine tract (Q-tract). This tract is encoded by a CAG trinucleotide repeat and varies from 8 to 33 codons in the healthy population. Q-tract length is inversely correlated with AR transcriptional activity in vitro, but whether endogenous androgen action is affected is not consistently supported by...

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Identifiers

PMID: 21664242
DOI: 10.1016/j.mce.2011.05.011
PMCID: PMC3148310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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