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Article

Structural and functional consequences of glutamine tract variation in the androgen receptor.

Human molecular genetics - 15 Aug 2004

Buchanan Grant, Yang Miao, Cheong Albert, Harris Jonathan M, Irvine Ryan A, Lambert Paul F, Moore Nicole L, Raynor Michael, Neufing Petra J, Coetzee Gerhard A, Tilley Wayne D

Abstract excerpt

The androgen receptor (AR) gene contains a polymorphic trinucleotide repeat region, (CAG)(n), in its N-terminal transactivation domain (NTD) that encodes a polyglutamine (polyQ) tract in the receptor protein. Whereas the length of the CAG repeat ranges from 6 to 39 in healthy individuals, the variations in repeat length both within and outside the normal range are associated with disease, including impaired...

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Source

Identifiers

PMID: 15198988
DOI: 10.1093/hmg/ddh181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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