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Article

Interleukin-1 beta gene polymorphism and its interactions with neuregulin-1 gene polymorphism are associated with schizophrenia.

European archives of psychiatry and clinical neuroscience - 1 Feb 2008

Hänninen Kari, Katila Heikki, Saarela Marika, Rontu Riikka, Mattila Kari M, Fan Meng, Hurme Mikko, Lehtimäki Terho

Abstract excerpt

Interleukin-1beta (IL-1beta) and neuregulin-1 (NRG-1) have an important role in development of the central nervous system. Several recent studies suggest that their genetic polymorphisms are associated with schizophrenia. We studied the effects of the IL-1beta gene (IL-1B) -511 and NRG-1 SNP8NRG221533 polymorphisms and their interactions on the risk and age of onset of schizophrenia in 113 Finnish schizophrenic...

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PMID: 17901998
DOI: 10.1007/s00406-007-0756-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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