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Article

In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2010

Marballi Ketan, Quinones Marlon P, Jimenez Fabio, Escamilla Michael A, Raventós Henriette, Soto-Bernardini Maria Clara, Ahuja Seema S, Walss-Bass Consuelo

Abstract excerpt

Neuregulin 1 (NRG1) has been implicated in several disorders including breast cancer, multiple sclerosis, and schizophrenia. Also, recent evidence suggests that NRG1 may play a role in regulation of inflammation and immune system response. We therefore hypothesized that a schizophrenia-associated missense mutation (valine to leucine) we identified within the transmembrane region of NRG1 would also be linked to...

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Source

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Identifiers

PMID: 20625696
DOI: 10.1007/s00109-010-0653-y
PMCID: PMC2976656

Genes

NRG1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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