Article
Association study of functional polymorphisms in interleukins and interleukin receptors genes: IL1A, IL1B, IL1RN, IL6, IL6R, IL10, IL10RA and TGFB1 in schizophrenia in Polish population.
Schizophrenia research - 1 Dec 2015
Kapelski Pawel, Skibinska Maria, Maciukiewicz Malgorzata, Wilkosc Monika, Frydecka Dorota, Groszewska Agata, Narozna Beata, Dmitrzak-Weglarz Monika, Czerski Piotr, Pawlak Joanna, Rajewska-Rager Aleksandra, Leszczynska-Rodziewicz Anna, Slopien Agnieszka, Zaremba Dorota, Twarowska-Hauser Joanna
Abstract excerpt
Schizophrenia has been associated with a large range of autoimmune diseases, with a history of any autoimmune disease being associated with a 45% increase in risk for the illness. The inflammatory system may trigger or modulate the course of schizophrenia through complex mechanisms influencing neurodevelopment, neuroplasticity and neurotransmission. In particular, increases or imbalance in cytokine before birth...
Topics
- Adult
- Family
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Interleukin 1 Receptor Antagonist Protein