Article
Interleukin 1 beta gene and risk of schizophrenia: detailed case-control and family-based studies and an updated meta-analysis.
Human psychopharmacology - 1 Jan 2014
Shibuya Masako, Watanabe Yuichiro, Nunokawa Ayako, Egawa Jun, Kaneko Naoshi, Igeta Hirofumi, Someya Toshiyuki
Abstract excerpt
OBJECTIVE: Interleukin-1 beta (IL-1β) has been implicated in the pathophysiology of schizophrenia. To assess whether the IL1B gene confers increased susceptibility to schizophrenia, we conducted case-control and family-based studies and an updated meta-analysis. METHODS: We tested the association between IL1B and schizophrenia in 1229 case-control and 112 trio samples using 12 markers, including common tagging...
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