Article
Association between IL-1beta -511C/T and IL-1RA (86bp)n repeats polymorphisms and schizophrenia.
Journal of psychiatric research - 1 Jan 2000
Zanardini Roberta, Bocchio-Chiavetto Luisella, Scassellati Catia, Bonvicini Cristian, Tura Gian Battista, Rossi Giuseppe, Perez Jorge, Gennarelli Massimo
Abstract excerpt
It has been established that cytokines play a critical role in the regulation of the CNS and recent studies have suggested that dysfunctions of both pro-inflammatory (IL-1beta, IL-6, and TNF-alpha) and anti-inflammatory (IL-1RA and IL-10) cytokines could be involved in the pathophysiology of schizophrenia. Previous studies have reported that functional polymorphisms in some cytokines genes may have important...
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