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Article

Genetic variants in transforming growth factor-β gene (TGFB1) affect susceptibility to schizophrenia.

Molecular biology reports - 1 Oct 2013

Frydecka Dorota, Misiak Blazej, Beszlej Jan Aleksander, Karabon Lidia, Pawlak-Adamska Edyta, Tomkiewicz Anna, Partyka Anna, Jonkisz Anna, Kiejna Andrzej

Abstract excerpt

Immense body of evidence indicates that dysfunction of immune system is implicated in the etiology of schizophrenia. The immune theory of schizophrenia is supported by alterations in cytokine profile in the brain and peripheral blood. Given the strong genetic background of schizophrenia, it might be assumed that aberrant production of cytokines might be the consequence of genetic factors. This study aimed at...

Topics

Adult
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Interferon-gamma
Interleukin-2
Interleukin-6
Male
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizophrenia

Transforming Growth Factor beta1

Source

Open in PubMed Open full text

Identifiers

PMID: 24065520
DOI: 10.1007/s11033-013-2662-8
PMCID: PMC3824289

Genes

TGFB1
IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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