Article
Possible association between interleukin-1β gene and schizophrenia in a Japanese population.
Behavioral and brain functions : BBF - 16 Aug 2011
Sasayama Daimei, Hori Hiroaki, Teraishi Toshiya, Hattori Kotaro, Ota Miho, Iijima Yoshimi, Tatsumi Masahiko, Higuchi Teruhiko, Amano Naoji, Kunugi Hiroshi
Abstract excerpt
BACKGROUND: Several lines of evidence have implicated the pro-inflammatory cytokine interleukin-1beta (IL-1β) in the etiology of schizophrenia. Although a number of genetic association studies have been reported, very few have systematically examined gene-wide tagging polymorphisms. METHODS: A total of 533 patients with schizophrenia (302 males: mean age ± standard deviation 43.4 ± 13.0 years; 233 females; mean...
Topics
- Adult
- Asian People
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Interleukin-1beta
- Male
- Middle Aged
- Polymorphism, Single Nucleotide