Article
Polymorphisms of the interleukin-1 gene complex in schizophrenia.
Molecular psychiatry - 1 Mar 1999
Katila H, Hänninen K, Hurme M
Abstract excerpt
Activation of the inflammatory response system has been related to the pathophysiology of schizophrenia by several recent studies. Schizophrenic patients have varied levels of proinflammatory cytokines, such as interleukin (IL)-1, -6, and tumor necrosis factor (TNF)alpha in their peripheral blood or cerebrospinal fluid. These cytokines can modify the metabolism of neurotransmitters, influence neural development,...
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