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Article

Interaction between CD14 and LXRbeta genes modulates Alzheimer's disease risk.

Journal of the neurological sciences - 15 Jan 2008

Rodríguez-Rodríguez Eloy, Sánchez-Juan Pascual, Mateo Ignacio, Infante Jon, Sánchez-Quintana Coro, García-Gorostiaga Inés, Berciano José, Combarros Onofre

Abstract excerpt

A chronic inflammatory process with activation of microglial cells contribute to the neurodegeneration associated with Alzheimer's disease (AD). CD14 and LXRbeta are receptors involved in the regulation of inflammatory responses of microglia in response to bacterial infection or lipopolysaccharide stimulation. In a case-control study in 266 AD patients and 273 healthy controls, we examined whether the combined...

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Identifiers

PMID: 17900622
DOI: 10.1016/j.jns.2007.08.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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