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Article

CD14 receptor polymorphism and Alzheimer's disease risk.

Neuroscience letters - 1 Jan 2000

Combarros Onofre, Infante Jon, Rodríguez Eloy, Llorca Javier, Peña Nicolás, Fernández-Viadero Carlos, Berciano José

Abstract excerpt

Activation of microglial cells is involved in the inflammatory component of Alzheimer's disease (AD), and it may be triggered by infectious pathogens. CD14, a receptor upregulated in activated microglia, plays a central role in innate immunity through recognition of bacterial lipopolysaccharide and initiation of inflammatory response. A polymorphism in the promoter region (-260) of the CD14 receptor has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15854776
DOI: 10.1016/j.neulet.2005.01.082

Genes

APOE
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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