Article
Polymorphisms in inflammatory genes and the risk of Alzheimer disease.
Archives of neurology - 1 Nov 2001
McGeer P L, McGeer E G
Abstract excerpt
The concept of inflammation as a major factor in Alzheimer disease (AD) has heretofore been based on postmortem findings of autodestructive changes associated with the lesions coupled with epidemiological evidence of a protective effect of anti-inflammatory agents. Now there is evidence that the risk of AD is substantially influenced by a total of 10 polymorphisms in the inflammatory agents interleukin 1alpha,...
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