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Effect of Proinflammatory Gene Polymorphisms on the Risk of Alzheimer's Disease

5 Sept 2013

Abstract excerpt

BACKGROUND: A number of studies associate Alzheimer's disease (AD) with APOE polymorphism and alleles which favor the increased expression of immunological mediators such as cytokines or acute-phase proteins. OBJECTIVE: In this study we evaluated the distribution of a set of functionally important polymorphisms of genes encoding prototypical inflammatory molecules in individuals with AD. We also investigated...

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PMID: 24022074
DOI: 10.1159/000353395

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