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Article

Increased susceptibility of Sf1(+/-) mice to azoxymethane-induced colon tumorigenesis.

Cancer science - 1 Dec 2007

Shitashige Miki, Satow Reiko, Honda Kazufumi, Ono Masaya, Hirohashi Setsuo, Yamada Tesshi

Abstract excerpt

Aberrant transactivation of a certain set of target genes by the beta-catenin and T-cell factor-4 nuclear complex has been considered crucial for the initiation of colorectal carcinogenesis. We previously identified splicing factor-1 (SF1) as a novel component of the beta-catenin and T-cell factor-4 complex, and showed that the overexpression of SF1 inhibited the gene transactivational activity of the complex and...

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Identifiers

PMID: 17900258
DOI: 10.1111/j.1349-7006.2007.00629.x
PMCID: PMC11159411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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