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NSAID Activated Gene (NAG-1), a Modulator of Tumorigenesis

30 Nov 2006

Abstract excerpt

The NSAID activated gene (NAG-1), a member of the TGF-beta superfamily, is involved in tumor progression and development. The over-expression of NAG-1 in cancer cells results in growth arrest and increase in apoptosis, suggesting that NAG-1 has anti-tumorigenic activity. This conclusion is further supported by results of experiments with transgenic mice that ubiquitously express human NAG-1. These transgenic mice...

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PMID: 17129398
DOI: 10.5483/bmbrep.2006.39.6.649

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