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The signal pathways in azoxymethane-induced colon cancer and preventive implications

15 Jul 2009

Abstract excerpt

Colon cancer is the third most common cancer and third most common cause of cancer-related death in the USA according to 2008 American Cancer Society statistics. The carcinogenesis of colon cancer has been associated with both genetics and environmental factors. It has been found that several signal pathways, including K-ras, Src/PI3K/Akt, beta-catenin, TGFbeta and p53 play critical roles in its pathogenesis. The...

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PMID: 19502780
DOI: 10.4161/cbt.8.14.8983

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