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Article

Preliminary analysis of azoxymethane-induced colon tumorigenesis in mouse aggregation chimeras.

Carcinogenesis - 1 Apr 1999

Wang Q S, Walsh A, Goldsby J S, Papanikolaou A, Bolt A B, Rosenberg D W

Abstract excerpt

Inbred mice exhibit differential susceptibility to colon carcinogens. The following study addresses the possibility that differences are intrinsic to colonic mucosa (cell autonomous) or are mediated by extracolonic systemic factors (e.g. liver activation of carcinogens). Our approach was to construct mouse aggregation chimeras, mice whose tissues are a mosaic of cells derived from two parental genotypes, from a...

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Source

Identifiers

PMID: 10223201
DOI: 10.1093/carcin/20.4.691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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