Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis.

Oncogene - 7 Sept 2006

Leung N, Turbide C, Olson M, Marcus V, Jothy S, Beauchemin N

Abstract excerpt

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a glycoprotein that is part of the carcinoembryonic antigen and the immunoglobulin superfamilies. We have shown that it functions as a tumor suppressor and that this function depends upon the presence of the longer CEACAM1 cyt...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Azoxymethane
Share to Blotting, Western
Share to Carcinoembryonic Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinogens

Share to Colonic Neoplasms

Share to Cyclin-Dependent Kinase Inhibitor p21

Share to Cyclin-Dependent Kinase Inhibitor p27

Share to Gene Targeting

Source

Identifiers

PMID: 16619040
DOI: 10.1038/sj.onc.1209541

Genes

CEACAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16619040-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis.PMID 16619040Read ↗

The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis.Semantic proximity Read ↗

Increased colon tumor susceptibility in azoxymethane treated CEABAC transgenic mice.Semantic proximity Read ↗

Genetic alterations and expression pattern of CEACAM1 in colorectal adenomas and cancers.Semantic proximity Read ↗

Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.Semantic proximity Read ↗

Differences in tissue-specific and embryonic expression of mouse Ceacam1 and Ceacam2 genesSemantic proximity Read ↗

CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo.Semantic proximity Read ↗

Loss of expression of the tumor suppressor CEACAM1 links different hereditary colorectal carcinoma subtypes to the genesis of sporadic colorectal carcinoma.Semantic proximity Read ↗

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice.Semantic proximity Read ↗

Altered splicing of CEACAM1 in breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoformsSemantic proximity Read ↗

TMIGD1, a putative tumor suppressor, induces G2-M cell cycle checkpoint arrest in colon cancer cellsSemantic proximity Read ↗

Expression of transgenic carcinoembryonic antigen (CEA) in tumor-prone mice: an animal model for CEA-directed tumor immunotherapy.Semantic proximity Read ↗

Loss of p27Kip1 leads to expansion of CD4+ effector memory T cells and accelerates colitis-associated colon cancer in mice with a T cell lineage restricted deletion of Smad4Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.