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Article

The zinc cluster transcription factor Tac1p regulates <i>PDR16</i> expression in <i>Candida albicans</i>

25 Sept 2007

Abstract excerpt

The Candida albicans PDR16 gene, encoding a putative phosphatidylinositol transfer protein, is co-induced with the multidrug transporter genes CDR1 and CDR2 in azole-resistant (A(R)) clinical isolates and upon fluphenazine exposure of azole-susceptible (A(S)) cells, suggesting that it is regulated by Tac1p, the transcriptional activator of CDR genes. Deleting TAC1 in an A(R) isolate (5674) overexpressing PDR16,...

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PMID: 17897373
DOI: 10.1111/j.1365-2958.2007.05931.x

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Related research

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The zinc cluster transcription factor Tac1p regulates <i>PDR16</i> expression in <i>Candida albicans</i>PMID 17897373Read ↗

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