Article
dAP-2 and defective proventriculus regulate Serrate and Delta expression in the tarsus of Drosophila melanogaster.
Genome - 1 Aug 2007
Ciechanska Ewa, Dansereau David A, Svendsen Pia C, Heslip Tim R, Brook William J
Abstract excerpt
The segmentation of the proximal-distal axis of the Drosophila melanogaster leg depends on the localized activation of the Notch receptor. The expression of the Notch ligand genes Serrate and Delta in concentric, segmental rings results in the localized activation of Notch, which induces joint formation and is required for the growth of leg segments. We report here that the expression of Serrate and Delta in the...
Topics
- Animals
- Calcium-Binding Proteins
- Digestive System Abnormalities
- Drosophila Proteins
- Drosophila melanogaster
- Extremities
- Gene Expression Regulation, Developmental
- Genes, Reporter
- Immunohistochemistry
- Intercellular Signaling Peptides and Proteins
- Intracellular Signaling Peptides and Proteins
- Jagged-1 Protein