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Article

Notch signaling relieves the joint-suppressive activity of Defective proventriculus in the Drosophila leg.

Developmental biology - 1 Dec 2007

Shirai Tetsuya, Yorimitsu Takeshi, Kiritooshi Naruto, Matsuzaki Fumio, Nakagoshi Hideki

Abstract excerpt

Segmentation plays crucial roles during morphogenesis. Drosophila legs are divided into segments along the proximal-distal axis by flexible structures called joints. Notch signaling is necessary and sufficient to promote leg growth and joint formation, and is activated in distal cells of each segment in everting prepupal leg discs. The homeobox gene defective proventriculus (dve) is expressed in regions both...

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PMID: 17950268
DOI: 10.1016/j.ydbio.2007.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Notch signaling relieves the joint-suppressive activity of Defective proventriculus in the Drosophila leg.PMID 17950268Read ↗

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