Article
Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.
Genes & development - 15 Feb 1996
Doherty D, Feger G, Younger-Shepherd S, Jan L Y, Jan Y N
Abstract excerpt
Wing margin formation in Drosophila requires the Notch receptor and, in the dorsal compartment, one of its ligands, Serrate. We provide evidence that Delta, the other known ligand for Notch, is also essential for this process. Delta is required in ventral cells at the dorsal/ventral compartment b...
Topics
- Animals
- Calcium-Binding Proteins
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Histocytochemistry
- Intercellular Signaling Peptides and Proteins
- Intracellular Signaling Peptides and Proteins
- Jagged-1 Protein
- Membrane Proteins
- Models, Genetic
- Phenotype
- Proto-Oncogene Proteins
- Receptors, Notch
- Serrate-Jagged Proteins
- Signal Transduction
- Wings, Animal
- Wnt1 Protein