Phenotypic and molecular characterization of SerD, a dominant allele of the Drosophila gene Serrate.

doi:10.1093/genetics/139.1.203

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Article

Phenotypic and molecular characterization of SerD, a dominant allele of the Drosophila gene Serrate.

Genetics - 1 Jan 1995

Thomas U, Jönsson F, Speicher S A, Knust E

Abstract excerpt

The Drosophila gene Serrate (Ser) encodes a transmembrane protein with 14 epidermal growth factor--like repeats in its extracellular domain, which is required for the control of cell proliferation and pattern formation during wing development. Flies hetero- or homozygous for the dominant mutation...

Topics

Alleles
Animals
Base Sequence
Calcium-Binding Proteins
Drosophila
Drosophila Proteins
Genes, Dominant
Genes, Insect
Genomic Library
Immunohistochemistry
In Situ Hybridization
Insect Hormones
Intercellular Signaling Peptides and Proteins
Jagged-1 Protein
Membrane Proteins
Molecular Sequence Data
Mutagenesis, Insertional
Phenotype

Source

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Identifiers

PMID: 7705624
DOI: 10.1093/genetics/139.1.203
PMCID: PMC1206319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7705624-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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