The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs.

doi:10.1242/dev.111.3.749

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Article

The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs.

Development (Cambridge, England) - 1 Mar 1991

Thomas U, Speicher S A, Knust E

Abstract excerpt

We describe the molecular characterization of the Drosophila gene Serrate (Ser), which encodes an integral membrane protein. The extracellular domain contains two cysteine-rich regions, one of which is organized in a tandem array of 14 EGF-like repeats. Antibodies directed against part of the ext...

Topics

Amino Acid Sequence
Animals
Base Sequence
Drosophila
Epidermal Growth Factor
Membrane Proteins
Microscopy, Immunoelectron
Molecular Probe Techniques
Molecular Sequence Data
Phenotype
Wings, Animal

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