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Article

G protein-coupled receptor 83 is dispensable for the development and function of regulatory T cells.

Molecular and cellular biology - 1 Dec 2007

Lu Li-Fan, Gavin Marc A, Rasmussen Jeffrey P, Rudensky Alexander Y

Abstract excerpt

Global analyses of gene expression in regulatory T (Treg) cells, whose development is critically dependent upon the transcription factor Foxp3, have provided many clues as to the molecular mechanisms these cells employ to control immune responses and establish immune tolerance. Through these studies, G protein-coupled receptor 83 (GPR83) was found to be expressed at high levels in Treg-cell populations. However,...

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Source

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Identifiers

PMID: 17893329
DOI: 10.1128/MCB.01075-07
PMCID: PMC2169173

Genes

GPR83

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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