Article
Inflammation in vivo is modulated by GPR83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cells.
Genes and immunity - 1 Jun 2010
Hansen W, Westendorf A M, Toepfer T, Mauel S, Geffers R, Gruber A D, Buer J
Abstract excerpt
Most recently, we have described the G-protein coupled receptor 83 (GPR83), which is highly expressed by CD4(+)CD25(+) regulatory T cells (Tregs) to be involved in the induction of CD4(+)Foxp3(+) Tregs in the course of an ongoing immune response. Four GPR83 isoforms have been described. Here, we...
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