Article

Novel role of GPR109A in thymic regulatory T cell development

2023-02-23

Abstract excerpt

<title>Abstract</title> <p>Regulatory T cells (Treg) maintain immune homeostasis due to their anti-inflammatory functions. They can be generated either centrally in the thymus or in peripheral organs. Metabolites such as short chain fatty acids produced by intestinal microbiota can induce peripheral Treg differentiation, by activating G-protein-coupled-receptors like GPR109A. In this study, we identified a novel...

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Literature Corpus work: d323c9b7-9001-5768-87fb-fd43c04cb973
DOI: 10.21203/rs.3.rs-2609653/v1

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