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Article

A function for interleukin 2 in Foxp3-expressing regulatory T cells.

Nature immunology - 1 Nov 2005

Fontenot Jason D, Rasmussen Jeffrey P, Gavin Marc A, Rudensky Alexander Y

Abstract excerpt

Regulatory T cells (T(reg) cells) expressing the forkhead family transcription factor Foxp3 are critical mediators of dominant immune tolerance to self. Most T(reg) cells constitutively express the high-affinity interleukin 2 (IL-2) receptor alpha-chain (CD25); however, the precise function of IL...

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Identifiers

PMID: 16227984
DOI: 10.1038/ni1263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16227984-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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