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Article

Is FOXP3 a bona fide marker for human regulatory T cells?

European journal of immunology - 1 Apr 2008

Roncarolo Maria-Grazia, Gregori Silvia

Abstract excerpt

FOXP3 is a specific marker for naturally occurring regulatory T cells (nTreg). FOXP3 expression is correlated with development and function of nTreg. Recent evidence suggests that, upon activation, human effector T (Teff) cells and type 1 regulatory T (Tr1) cells can express FOXP3, albeit transiently. While the role of transient FOXP3 expression in Teff cells is poorly understood, it is becoming clear that it...

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Identifiers

PMID: 18395862
DOI: 10.1002/eji.200838168

Genes

FOXP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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