Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of a CXCL9 polymorphism with pediatric Crohn's disease.

Biochemical and biophysical research communications - 23 Nov 2007

Lacher Martin, Kappler Roland, Berkholz Stefan, Baurecht Hansjoerg, von Schweinitz Dietrich, Koletzko Sibylle

Abstract excerpt

Genetic and environmental factors contribute to the etiopathogenesis of Crohn's disease (CD) and ulcerative colitis (UC). To identify new susceptibility genes, we determined the mRNA expression level of 88 genes from different biological contexts on colonic biopsies of CD and UC patients. We show that CXCL9 was overexpressed in colonic tissue of 3/5 CD and 3/3 UC patients compared to healthy controls. SNP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crohn Disease

Share to Gene Frequency

Share to Inflammatory Bowel Diseases

Share to Odds Ratio

Share to Polymorphism, Genetic

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 17892861
DOI: 10.1016/j.bbrc.2007.09.020

Genes

CXCL9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of a CXCL9 polymorphism with pediatric Crohn's disease.PMID 17892861Read ↗

Strong overexpression of CXCR3 axis components in childhood inflammatory bowel disease.Semantic proximity Read ↗

Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children.Semantic proximity Read ↗

Profiling Non-Coding RNA Levels With Clinical Classifiers in Pediatric Crohn’s DiseaseSemantic proximity Read ↗

Genetic Risk for Inflammatory Bowel Disease Is a Determinant of Crohn's Disease Development in Chronic Granulomatous Disease.Semantic proximity Read ↗

Is a rare CXCL8 gene variant a new possible cause or course factor of inflammatory bowel disease?Semantic proximity Read ↗

STAT3 genotypic variation and cellular STAT3 activation and colon leukocyte recruitment in pediatric Crohn disease.Semantic proximity Read ↗

Linking Gene Expression to Clinical Outcomes in Pediatric Crohn’s Disease Using Machine LearningSemantic proximity Read ↗

Interleukin 10 (IL-10) gene variants and susceptibility for paediatric onset Crohn's disease.Semantic proximity Read ↗

KCNN4 gene variant is associated with ileal Crohn's Disease in the Australian and New Zealand population.Semantic proximity Read ↗

Aberrant miR-29 is a predictive feature of severe phenotypes in pediatric Crohn’s diseaseSemantic proximity Read ↗

Expression profile of genes involved in pathogenesis of pediatric Crohn's disease.Semantic proximity Read ↗

Aberrant miR-29 is a predictive feature of severe phenotypes in pediatric Crohn's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.