Article

Aberrant miR-29 is a predictive feature of severe phenotypes in pediatric Crohn’s disease

2022-12-19

Abstract excerpt

Crohn’s disease (CD) is a chronic inflammatory gut disorder. Molecular mechanisms underlying the clinical heterogeneity of CD remain poorly understood. MicroRNAs (miRNAs) are important regulators of gut physiology and several have been implicated in the pathogenesis of adult CD. However, there is a dearth of large-scale miRNA studies for pediatric CD. We hypothesized that specific miRNAs uniquely mark pediatric CD...

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Literature Corpus work: 135ee51d-c3be-5072-801a-fb76410a93b4
DOI: 10.1101/2022.12.16.520635

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