Article
Expression profile of genes involved in pathogenesis of pediatric Crohn's disease.
Journal of gastroenterology and hepatology - 1 Jun 2012
Sim Winnie H, Wagner Josef, Cameron Donald J, Catto-Smith Anthony G, Bishop Ruth F, Kirkwood Carl D
Abstract excerpt
BACKGROUND AND AIM: Expression profiling of genes specific to pediatric Crohn's Disease (CD) patients was performed to elucidate the molecular mechanisms underlying disease cause and pathogenesis at disease onset. METHODS: We used suppressive subtractive hybridization (SSH) and differential screening analysis to profile the mRNA expression patterns of children with CD and age- and sex-matched controls without...
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