Article
One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study.
Cancer science - 1 Sept 2007
Suzuki Takeshi, Matsuo Keitaro, Hasegawa Yasuhisa, Hiraki Akio, Wakai Kenji, Hirose Kaoru, Saito Toshiko, Sato Shigeki, Ueda Ryuzo, Tajima Kazuo
Abstract excerpt
Low consumption of vegetables and fruits, which leads to insufficient folate intake, is associated with increased risk of several types of cancer, including head and neck squamous cell carcinoma (HNSCC). Functional polymorphisms in genes encoding one-carbon metabolism enzymes, such as methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MTR A2756G), methionine synthase reductase...
Topics
- 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
- Aged
- Alcohol Drinking
- Carbon
- Carcinoma, Squamous Cell
- Case-Control Studies
- Diet
- Female
- Ferredoxin-NADP Reductase
- Folic Acid