Analysis of the complete hepatitis B virus genome in patients with genotype C chronic hepatitis and hepatocellular carcinoma.

doi:10.1111/j.1349-7006.2007.00609.x

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Article

Analysis of the complete hepatitis B virus genome in patients with genotype C chronic hepatitis and hepatocellular carcinoma.

Cancer science - 1 Dec 2007

Zhang Kai Yu, Imazeki Fumio, Fukai Kenichi, Arai Makoto, Kanda Tatsuo, Mikata Rintaro, Yokosuka Osamu

Abstract excerpt

Hepatitis B virus (HBV) genotype C and the basic core promoter (BCP) mutations were reported to be associated with the development of hepatocellular carcinoma (HCC). In this study the full sequences of HBV genomes were analyzed in order to find the other predictors of HCC development. We determined the full sequences of HBV genomes in 24 genotype C carriers who developed HCC (HCC group) at the beginning of...

Topics

Adult
Amino Acid Substitution
Carcinoma, Hepatocellular
Cell Line, Tumor
DNA, Viral
Female
Genes, Reporter
Genome, Viral
Genotype
Hepatitis B virus
Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Liver Neoplasms

Male

Middle Aged

Polymorphism, Single Nucleotide

RNA, Viral

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 17888035
DOI: 10.1111/j.1349-7006.2007.00609.x
PMCID: PMC11158307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17888035-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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